Product Areas
XPO6 Antibody
Product Details
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
1125aa,129 kDa |
Observed molecular
weight |
135 kDa |
|
GenBank accession number |
BC014071 | Gene ID (NCBI) | 23214 |
| Gene symbol | XPO6 | Synonyms | EXP6, exportin 6, FLJ22519, KIAA0370, Ran binding protein 20, RANBP20, XPO6 |
Background
Human XPO6 gene encodes a Ran-binding protein 20, exportin-6, belonging to the exportin family. Exportin-6 shuttles between the nucleus and the cytoplasm and mediates the nuclear export of actin and profilin-actin complexes in somatic cells. Interaction of exportin-6 and actin is achieved in a RanGTP-dependent manner, actin is a major cytoskeletal element which is normally kept cytoplasmic by exportin-6 driven nuclear export. |