Product Areas
XPR1 Antibody
Product Details
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
696aa, 82 kDa |
Observed molecular
weight |
82-84 kDa |
|
GenBank accession number |
BC041142 | Gene ID (NCBI) | 9213 |
| Gene symbol | XPR1 | Synonyms | FLJ90308, Protein SYG1 homolog, SYG1, X receptor, X3, XPR1, XR |
Background
XPR1 is a receptor for xenotropic and polytropic murine leukemia retroviruses and homolog of yeast Syg1 and plant Pi transporter PHO1 (PMID: 20633538). XPR1 has been identifies as an atypical G-protein-coupled receptor. Xenotropic or polytropic retrovirus binding to XPR1 can disrupt the cAMP-mediated signaling function of Xpr1, leading to the apoptosis of infected cells (PMID: 22090134). |