Product Areas
XRCC4 Antibody
Product Details
Product Information
| Source: | Rabbit | Purify: | Antigen affinity purification |
| IsoType: | IgG | Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Immunogen Information
|
Caculated Molecular Weight: |
310aa,35 kDa |
Observed Molecular
Weight: |
55kd |
| GenbankNo | BC005259 | GeneID: | 7518 |
| Symbol | XRCC4 | Synonyms | DNA repair protein XRCC4, XRCC4 |
Background
There are at least two pathways for eukaryotes to repair DNA double-strand breaks: homologous recombination and nonhomologous end joining(NHEJ). XRCC4 is one of the core machiney of NHEJ that requied for double-strand break repair and V(D)J recombination. The DNA ligase IV(LIG4)-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. |