YWHAZ Antibody
Product Details
Source | Rabbit | Purification method | Antigen affinity purification |
Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Calculated molecular weight |
28 kDa |
Observed molecular
weight |
28-30 kDa |
GenBank accession number |
BC003623 | Gene ID (NCBI) | 7534 |
Gene symbol | YWHAZ | Synonyms | 14 3 3 protein zeta/delta, 14-3-3, KCIP 1, YWHAZ |
YWHAZ (also known as 14-3-3 zeta) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody was raised against the full-length YWHAZ. |