Product Areas
ZC3H12D Antibody
Product Details
Product Information
Source | Rabbit | Purification method | Antigen affinity purification |
Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
Calculated molecular weight |
527aa,58 kDa |
Observed molecular
weight |
55-58 kDa |
GenBank accession number |
BC157832 | Gene ID (NCBI) | 340152 |
Gene symbol | ZC3H12D | Synonyms | C6orf95, dJ281H8.1, FLJ46041, MCP induced protein 4, MCPIP4, p34, Probable ribonuclease ZC3H12D, TFL, ZC3H12D |
Background
ZC3H12D, also named as MCP induced protein 4, is a 527 amino acid protein, which contains one C3H1-type zinc finger and belongs to the ZC3H12 family. ZC3H12D exists as three isoforms and localizes in the cytoplasm. ZC3H12D may regulate cell growth likely by suppressing RB1 phosphorylation and serves as a tumor suppressor in certain leukemia cells. ZC3H12D is expressed in normal human lymphocytes but defective in some leukemia/lymphoma cell lines. |