Product Areas
ZHX1 Antibody
Product Details
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
873aa,98 kDa |
Observed molecular
weight |
100-120 kDa |
|
GenBank accession number |
BC040481 | Gene ID (NCBI) | 11244 |
| Gene symbol | ZHX1 | Synonyms | ZHX1, zinc fingers and homeoboxes 1 |
Background
Binding of the nuclear factor-Y complex (NF-Y) to the inverted CCAAT-box interferes with transcription activation through nucleosome reorganization. The three homologous proteins forming the zinc-fingers and homeoboxes (ZHX) family interact with the activation domain of NF-Ya to repress ranscription [PMID:19348505,20509910]. Human zinc-fingers and homeoboxes 1 (ZHX1) was cloned as a protein that interacts with the activation domain (AD) of the A subunit of nuclear factor-Y (NF-YA) [PMID:12237128]. |