Product Areas
ZMPSTE24 Antibody
Product Details
Product Information
Source | Rabbit | Purification method | Antigen affinity purification |
Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
Calculated molecular weight |
475aa,55 kDa |
Observed molecular
weight |
55 kDa |
GenBank accession number |
BC037283 | Gene ID (NCBI) | 10269 |
Gene symbol | ZMPSTE24 | Synonyms | CAAX prenyl protease 1 homolog, FACE 1, FACE1, FLJ14968, STE24, Ste24p, ZMPSTE24 |
Background
ZMPSTE24(CAAX prenyl protease 1 homolog) gene encodes a zinc metalloproteinase involved in the processing of farnesylated proteins(PubMed: 10373325). The significance of ZMPSTE24 in human disease stems from its role as an enzyme necessary for the correct processing and maturation of lamin A ,an intermediate filament component of the nuclear envelope (PubMed: 16297189). |