Product Areas
MSH2 Antibody
Product Details
Product Information
| Source: | Mouse | Purify: | Caprylic acid/ammonium sulfate precipitation |
| IsoType: | IgG1 | Storage: | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Immunogen Information
|
Caculated Molecular Weight: |
105 kDa |
Observed Molecular
Weight: |
100-105 kDa |
| GenbankNo | BC021566 | GeneID: | 4436 |
| Symbol | MSH2 | Synonyms | COCA1, FCC1, hMSH2, HNPCC, HNPCC1, LCFS2, MSH2, MutS protein homolog 2 |
Background
MSH2, named for its homologous to the E.coli MutS gene, takes part in DNA mismatch repair(MMR) to maintain the stability of DNA. MSH2 contains a helix-turn-helix domain, which responds for binding to DNA. Also, MSH2 has a direct role in mutation avoidance and micro-satellite stability in cell. |