Product Areas
MSH6 Antibody
Product Details
Product Information
Source | Mouse | Purification method | Protein A purification |
Isotype | IgG2a | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
Calculated molecular weight |
153 kDa |
Observed molecular
weight |
160 kDa |
GenBank accession number |
BC004246 | Gene ID (NCBI) | 2956 |
Gene symbol | MSH6 | Synonyms | G/T mismatch binding protein, GTBP, GTMBP, hMSH6, HNPCC5, HSAP, MSH6, MutS alpha 160 kDa subunit, mutS homolog 6 (E. coli), p160 |
Background
MSH6, also named as DNA mismatch repair protein Msh6 or GTMBP, is a 1360 amino acid protein, which contains one PWWP domain and belongs to the DNA mismatch repair MutS family. MSH6 localizes in the nucleus and is a component of the post-replicative DNA mismatch repair system. Msh2 and Msh6 form a protein complex required to repair mismatches generated during DNA replication. |