Product Areas
NAPRT1 Antibody
Product Details
Product Information
| Source | Mouse | Purification method | Protein A purification |
| Isotype | IgG2a | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
514aa,55 kDa |
Observed molecular
weight |
51 kDa |
|
GenBank accession number |
BC032466 | Gene ID (NCBI) | 93100 |
| Gene symbol | NAPRT1 | Synonyms | FHA HIT interacting protein, FHIP, NAPRT1, NAPRTase, PP3856 |
Background
Nicotinic acid (NA) is a coenzyme in cellular redox reactions, and is an essential component of metabolic pathways in all living cells. NAPRT1 (Nicotinate phosphoribosyltransferase) is essential for increasing cellular NAD levels and, thus, to prevent oxidative stress of cells. NAPRT1 converts Nicotinic acid (NA; niacin) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD). |