Product Areas
NR1H3 Antibody
Product Details
Product Information
| Source: | Mouse | Purify: | Caprylic acid/ammonium sulfate precipitation |
| IsoType: | IgG1 | Storage: | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Immunogen Information
|
Caculated Molecular Weight: |
50 kDa |
Observed Molecular
Weight: |
50 kDa 44 kDa |
| GenbankNo | BC041172 | GeneID: | 10062 |
| Symbol | NR1H3 | Synonyms | Liver X receptor alpha, LXR a, LXRA, NR1H3, Oxysterols receptor LXR alpha, RLD 1 |
Background
NR1H3, also known as LXRA, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation.. It's also a ligand-activated LXRs and forms heterodimers with retinoid X receptor, then participates in regulating expression of target genes containing LXR response elements. |