Product Areas
NUMBL Antibody
Product Details
Product Information
Source: | Mouse | Purify: | Protein A purification |
IsoType: | IgG2a | Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Immunogen Information
Caculated Molecular Weight: |
65 kDa |
Observed Molecular
Weight: |
70 kDa |
GenbankNo | BC001794 | GeneID: | 9253 |
Symbol | NUMBL | Synonyms | CAG3A, CTG3a, NBL, numb homolog (Drosophila) like, Numb like protein, NUMB R, Numb related protein, NUMBL, NUMBLIKE, NUMBR, TNRC23 |
Background
Numbl (also known as numblike or Nbl), as a conserved homolog of Drosophila Numb, is specfically expressed in the brain. Numbl is a cytoplasm protein and has redundant functions in embryonic neurogenesis. It plays an important role in ependymal wall integrity and subventricular zone neuroblast survival. However, its expression and function in the central nervous system lesion are still unclear. |