Product Areas
Occludin Antibody
Product Details
Product Information
| Source | Mouse | Purification method | Protein G purification |
| Isotype | IgG1 | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
522aa,59 kDa |
Observed molecular
weight |
59 kDa |
|
GenBank accession number |
BC029886 | Gene ID (NCBI) | 4950 |
| Gene symbol | OCLN | Synonyms | Occludin, OCLN |
Background
Occludin is an integral membrane protein located at the tight junction. It is a tetraspanin protein with four transmembrane domains, intracellular N and C termini and two extracellular loops. Occludin plays a role in the formation and regulation of the tight junction paracellular permeability barrier. Occludin can exist in different isoforms, owing to modifications at the posttranscriptional and posttranslational levels (PMID: 22083955). |