Product Areas
ORAI1 Antibody
Product Details
Product Information
Source | Mouse | Purification method | Protein A purification |
Isotype | IgG2a | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
Calculated molecular weight |
301aa,33 kDa |
Observed molecular
weight |
32 kDa |
GenBank accession number |
BC015369 | Gene ID (NCBI) | 84876 |
Gene symbol | ORAI1 | Synonyms |
Background
Store-operated calcium channels (SOCs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of SOCs. Orai1 protein is a 32-55 kDa plasma membrane protein with 4 transmembrane domains. Human patients with a severe combinaed immunodeficiency (SCID) syndrome possess point mutations in Orai1 gene. |