ORAI1 Antibody

Product Details


Product Information
Source Mouse Purification method Protein A purification
Isotype IgG2a Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Calculated molecular
weight
301aa,33 kDa Observed molecular
weight
32 kDa
GenBank accession
number
BC015369 Gene ID (NCBI) 84876
Gene symbol ORAI1 Synonyms
Background

Store-operated calcium channels (SOCs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of SOCs. Orai1 protein is a 32-55 kDa plasma membrane protein with 4 transmembrane domains. Human patients with a severe combinaed immunodeficiency (SCID) syndrome possess point mutations in Orai1 gene.

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