Product Areas
PDGFRA Antibody
Product Details
Product Information
Source | Mouse | Purification method | Caprylic acid/ammonium sulfate precipitation |
Isotype | IgG1 | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
Calculated molecular weight |
123 kDa |
Observed molecular
weight |
100-120 kDa, 140-160 kDa |
GenBank accession number |
BC015186 | Gene ID (NCBI) | 5156 |
Gene symbol | PDGFRA | Synonyms | CD140A, CD140a antigen, PDGF R alpha, PDGF receptor alpha, PDGFR2, PDGFRA, PDGFRα, PDGFR-α, Rhe PDGFRA |
Background
Platelet-derived growth factor receptor alpha (PDGFRA, also known as CD140a) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA is implicated in the regulation of embryonic development, tumorigenesis, cell proliferation, survival and chemotaxis. Mutations in PDGFRA gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. |