PDGFRA Antibody

Product Details


Product Information
Source Mouse Purification method Caprylic acid/ammonium sulfate precipitation
Isotype IgG1 Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Calculated molecular
weight
123 kDa Observed molecular
weight
100-120 kDa, 140-160 kDa
GenBank accession
number
BC015186 Gene ID (NCBI) 5156
Gene symbol PDGFRA Synonyms CD140A, CD140a antigen, PDGF R alpha, PDGF receptor alpha, PDGFR2, PDGFRA, PDGFRα, PDGFR-α, Rhe PDGFRA
Background

Platelet-derived growth factor receptor alpha (PDGFRA, also known as CD140a) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA is implicated in the regulation of embryonic development, tumorigenesis, cell proliferation, survival and chemotaxis. Mutations in PDGFRA gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Powered by AKCMS