Product Areas
Pikachurin Antibody
Product Details
Product Information
| Source: | Mouse | Purify: | Protein G purification |
| IsoType: | IgG1 | Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Immunogen Information
|
Caculated Molecular Weight: |
111 kDa |
Observed Molecular
Weight: |
111 kDa, 55-60 kDa |
| GenbankNo | BC033177 | GeneID: | 133584 |
| Symbol | EGFLAM | Synonyms | Agrin like protein, AGRINL, AGRNL, EGFLAM, FLJ39155, Pikachurin |
Background
Pikachurin, also known as EGFLAM or FLJ39155, is an extracellular matrix-like retinal protein that has been found to localize in the synaptic cleft of the photoreceptor ribbon synapse (PMID: 18641643). Pikachurin is a dystroglycan-interacting protein and has an essential role in photoreceptor ribbon synapse formation. Pikachurin is a 1017-amino-acid protein with a calculated molecular weight of 111 kDa and high mRNA abundance in retina. This monoclonal antibody detects two bands of 111 kDa and 55-60 kDa. The lower-molecular-weight band has been reported and likely represents a fragment resulting from cleavage of Pikachurin (PMID: 23226524). |