Product Areas
PLAA Antibody
Product Details
Product Information
| Source | Mouse | Purification method | Protein A purification |
| Isotype | IgG1 | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
738aa,81 kDa |
Observed molecular
weight |
75-80 kDa |
|
GenBank accession number |
BC032551 | Gene ID (NCBI) | 9373 |
| Gene symbol | PLAA | Synonyms | DOA1, FLJ11281, FLJ12699, PLA2P, PLAA, PLAP |
Background
Phospholipase A-2-activating protein (PLAA), also named PLAP, can interact with ubiquitin and is involved in the maintenance of ubiquitin levels. PLAA contains multiple consensus domains including WD repeats, PFU domain and PUL domain. Although the function of PLAA remains unclear, ubiquitin binding of PLAA might be the central role that connects ubiquitination and degradation in ERAD. Recent finding revealed that PLAA served as a novel nociveptive mediator after incision, and its expression level is regulated by miR-203. |