Product Areas
PTEN Antibody
Product Details
Product Information
| Source | Mouse | Purification method | Protein A purification |
| Isotype | IgG2a | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
47 kDa |
Observed molecular
weight |
55 kDa |
|
GenBank accession number |
BC005821 | Gene ID (NCBI) | 5728 |
| Gene symbol | PTEN | Synonyms | 10q23del, BZS, MHAM, MMAC1, phosphatase and tensin homolog, PTEN, PTEN1, TEP1 |
Background
PTEN (also designated MMAC1), products of tumor suppressor genes, are found deleted in most human gliomas. The PTEN genes are also mutated in many other tumors, such as brain, breast, kidney and prostate cancers. PTEN is a protein tyrosine phosphatase that may terminate the signaling transduction pathways mediated by PI 3-kinase/Akt. PTEN has an apparent molecular weight of 55 kDa and it is located in the cytosol. |