Product Areas
Rac1 Antibody
Product Details
Product Information
Source | Mouse | Purification method | Protein A purification |
Isotype | IgG2b | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
Calculated molecular weight |
21 kDa |
Observed molecular
weight |
21 kDa |
GenBank accession number |
BC004247 | Gene ID (NCBI) | 5879 |
Gene symbol | RAC1 | Synonyms | MIG5, p21 Rac1, RAC1, RAC1b, Ras like protein TC25, TC 25, TC25 |
Background
RAC1b, also named as TC25, belongs to the small GTPase superfamily and Rho family. RAC1 is a plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, it binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. |