Product Areas
SDCCAG8 Antibody
Product Details
Product Information
Source | Mouse | Purification method | Protein A purification |
Isotype | IgG2b | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
Calculated molecular weight |
713aa,83 kDa |
Observed molecular
weight |
83 kDa |
GenBank accession number |
BC032454 | Gene ID (NCBI) | 10806 |
Gene symbol | SDCCAG8 | Synonyms | Antigen NY CO 8, BBS16, CCCAP, hCCCAP, HSPC085, NY CO 8, SDCCAG8 |
Background
SDCCAG8, also named as CCCAP and NY-CO-8, plays a role in the establishment of cell polarity and epithelial lumen formation. It may play a role in ciliogenesis. Loss of SDCCAG8 function as a cause of a retinal-renal ciliopathy and validates exome capture analysis for broadly heterogeneous single-gene disorders. SDCCAG8 is localized at both centrioles and interacts directly with OFD1 (oral-facial-digital syndrome 1), which is associated with NPHP-RC. |