Product Areas
SEC5/EXOC2 Antibody
Product Details
Product Information
| Source: | Mouse | Purify: | Protein A purification |
| IsoType: | IgG2b | Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Immunogen Information
|
Caculated Molecular Weight: |
924aa,104 kDa |
Observed Molecular
Weight: |
100 kDa |
| GenbankNo | BC016918 | GeneID: | 55770 |
| Symbol | EXOC2 | Synonyms | EXOC2, exocyst complex component 2, Exocyst complex component Sec5, FLJ11026, SEC5, SEC5L1, Sec5p |
Background
EXOC2 (exocyst complex component 2), also known as SEC5 and SEC5L1, is a component of the exocyst complex, and is required to mediate RalB-dependent survival signals in transformed cells. The exocyst complex, composed of eight evolutionarily conserved subunits (SEC3, SEC5, SEC6, SEC8, SEC10, SEC15, EXO70, and EXO84), is involved in tethering post-Golgi secretory vesicles to specific plasma membrane domains. The gene of EXOC2 maps to chromosome 6p25.3, and encodes a 924-amino acid protein with an experimentally determined molecular mass of 95-100 kDa. EXOC2 mRNA is widely expressed with highest levels in brain and placenta. |