STMN3 Antibody
Product Details
Source: | Mouse | Purify: | Protein G purification |
IsoType: | IgG2b | Storage: | PBS with 0.0.2% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Caculated Molecular Weight: |
21 kDa |
Observed Molecular
Weight: |
21 kDa |
GenbankNo | BC009381 | GeneID: | 50861 |
Symbol | STMN3 | Synonyms | SCG10 like protein, SCLIP, Stathmin 3, stathmin like 3, STMN3 |
Stathmin family phosphoproteins participate in the control of microtubule dynamics and have been proposed to be involved in the control of neuronal differentiation. Neuron specific Stathmin-3 (STMN3) is a novel STAT3 (signal transducer and activator of transcription 3) interacting protein. STAT3 is a key contributor to cancer cell migration and invasion. STMN3 exhibits microtubule-destabilizing activity, which is antagonized by STAT3. SCG10 is a widely studied and recognized neuronal differentiation marker, STMN3 is a SCG10-like protein (SCLIP) and is present from the earliest stages of hippocampal neuron differentiation in culture at vesicle-like structures following dynamic microtubules. RNAi mediated inhibition of this gene resulted in increased axonal branching. |