Product Areas
TBL2 Antibody
Product Details
Product Information
| Source | Mouse | Purification method | Thiophilic affinity chromatograph |
| Isotype | IgA | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
446aa,50 kDa |
Observed molecular
weight |
50 kDa |
|
GenBank accession number |
BC012938 | Gene ID (NCBI) | 26608 |
| Gene symbol | TBL2 | Synonyms | DKFZp434N024, TBL2, transducin (beta) like 2, Transducin beta like protein 2, WBSCR13, WS betaTRP |
Background
TBL2 belongs to a member of the beta-transducin protein family. This gene is commonly deleted in Williams-Beuren syndrome, a developmental disorder with multi-system manifestations caused by haploinsufficiency for contiguous genes deleted in chromosome region 7q11.23. TBL2 encodes a protein with four putative WD40 repeats, which may be involved in some intracellular signaling pathway. |