Product Areas
TCN2 Antibody
Product Details
Product Information
| Source | Mouse | Purification method | Protein A purification |
| Isotype | IgG2b | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
400aa,44 kDa |
Observed molecular
weight |
43 kDa |
|
GenBank accession number |
BC011239 | Gene ID (NCBI) | 6948 |
| Gene symbol | TCN2 | Synonyms | TC 2, TC II, TC2, TCII, TCN2, Transcobalamin 2, Transcobalamin II |
Background
TCN2 (Transcobalamin-2) is a vitamin B12 (cobalamin; Cbl) binding and transport protein in plasma that facilitates the cellular uptake of the vitamin. TCN2 is secreted in a constitutive fashion in most cells. Plasma TCN2 levels have been reported to be elevated in a number of diverse human diseases. Defects in TCN2 are cause of transcobalamin-2 deficiency. (10714245) |