Product Areas
TINP1 Antibody
Product Details
Product Information
| Source | Mouse | Purification method | Protein G purification |
| Isotype | IgG1 | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
260aa,30 kDa |
Observed molecular
weight |
34 kDa |
|
GenBank accession number |
BC005288 | Gene ID (NCBI) | 10412 |
| Gene symbol | TINP1 | Synonyms | CDK105, Hairy cell leukemia protein 1, HCL G1, HUSSY29, NSA2, TINP1, YR 29 |
Background
TINP1 (TGF beta inducible nuclear protein 1) was widely expressed in various cell lines. TINP1 overexpression significantly promoted tumor cell proliferation, which may be associated with the downregulation of p53 expression. Furthermore, TINP1 promoted a number of cell lines to the S phase of the cell cycle. TINP1 promotes cell proliferation and significantly reduces p53 and p21 expression. |