Product Areas
TMEM70 Antibody
Product Details
Product Information
| Source | Mouse | Purification method | Protein A purification |
| Isotype | IgG2b | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
260aa,29 kDa |
Observed molecular
weight |
18 kDa |
|
GenBank accession number |
BC002748 | Gene ID (NCBI) | 54968 |
| Gene symbol | TMEM70 | Synonyms | FLJ20533, TMEM70, transmembrane protein 70 |
Background
TMEM70 belongs to the TMEM70 family. It is involved in biogenesis of mitochondrial ATP synthase. Defects in TMEM70 are a cause of mitochondrial encephalocardiomyopathy neonatal due to ATP synthase deficiency (MT-ATPSD). A publication (PMID:21147908) identified TMEM70 gene defect as a pan-ethnic disorder and further redefined it as the most common cause of nuclear-origin ATP synthase deficiency. |