Product Areas
transcription termination factor-Specific Antibody
Product Details
Product Information
| Source: | Mouse | Purify: | Protein A purification |
| IsoType: | IgG2a | Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Immunogen Information
| Immunogen: | Peptide | Full Name: | transcription termination factor, RNA polymerase I |
|
Caculated Molecular Weight: |
103 kDa |
Observed Molecular
Weight: |
106 kDa |
| GenbankNo | NM_007344 | GeneID: | 7270 |
| Symbol | TTF1 | Synonyms | TTF 1, TTF I, TTF1 |
Background
TTF1 is a multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. It plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5, TTF1 recovers DNA-binding activity. The antibody is specific to TTF1. |