HRP-conjugated beta Actin Antibody
Product Details
Source | Mouse | Purification method | Caprylic acid/ammonium sulfate precipitation |
Isotype | IgM | Storage | PBS with 0.02% Thimerosal, 50% Glycerol, pH 7.3. Store at -20oC. |
Immunogen | Recombinant Protein | Full name | actin, beta |
Calculated molecular weight |
375aa,42 kDa |
Observed molecular
weight |
42 kDa |
GenBank accession number |
BC002409 | Gene ID (NCBI) | 60 |
Gene symbol | ACTB | Synonyms | ACTB, Actin, actin, beta, Actin, cytoplasmic 1, B actin, Beta actin, F actin, HRP β actin, HRP-ACTB, HRP-Beta actin, HRP-F actin, PS1TP5BP1, β actin |
Beta actin, also named as ACTB and F-Actin, belongs to the actin family. Actins are highly conserved globular proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. At least six isoforms of actins are known in mammals and other vertebrates: alpha (ACTC1, cardiac muscle 1), alpha 1 (ACTA1, skeletal muscle) and 2 (ACTA2, aortic smooth muscle), beta (ACTB), gamma 1 (ACTG1) and 2 (ACTG2, enteric smooth muscle). Beta and gamma 1 are two non-muscle actin proteins. Most actins consist of 376aa, while ACTG2 (rich in muscles) has 375aa and ACTG1(found in non-muscle cells) has only 374aa. Beta actin has been widely used as the internal control in RT-PCR and Western Blotting as a 42-kDa protein. This antibody can recognize all of actins. This antibody is conjugated with HRP. |