XLF Antibody

Product Details


Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Calculated molecular
weight
299aa,33 kDa Observed molecular
weight
33 kDa
GenBank accession
number
BC030986 Gene ID (NCBI) 79840
Gene symbol NHEJ1 Synonyms FLJ12610, NHEJ1, Protein cernunnos, XLF, XRCC4 like factor
Background

XRCC4-like factor (XLF), also known as Cernunnos and NHEJ1, is a protein encoded by the human NHEJ1 gene and an important repair factor for DNA double-strand breaks. NHEJ is a well-known mechanism for the repair of double-strand breaks (DSBs), a lethal type of DNA damage in mammalian cells. It basically utilizes a group of enzymes to take hold of the ends of a broken DNA molecule, create a bridge between them, and subsequently re-ligate the broken DNA molecule. 

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