Product Areas
ZC3H12A Antibody
Product Details
Product Information
| Source: | Rabbit | Purify: | Antigen affinity purification |
| IsoType: | IgG | Storage: | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Immunogen Information
|
Caculated Molecular Weight: |
599aa,66 kDa |
Observed Molecular
Weight: |
66 kDa |
| GenbankNo | BC005001 | GeneID: | 80149 |
| Symbol | ZC3H12A | Synonyms | dJ423B22.1, FLJ23231, MCP induced protein 1, MCPIP, MCPIP1, Ribonuclease ZC3H12A, RP3 423B22.1, ZC3H12A |
Background
ZC3H12A, also named as MCPIP or MCPIP1, is a 599 amino acid protein, which contains one C3H1-type zinc finger and belongs to the ZC3H12 family. ZC3H12A localizes in the cytoplasm and nucleus. Increased expression of ZC3H12A is associated with ischemic heart disease. ZC3H12A has RNase activity and selectively degrades specific target mRNA species and modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. |