Product Areas
ZFYVE27 Antibody
Product Details
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
411aa,46 kDa |
Observed molecular
weight |
50kd |
|
GenBank accession number |
BC030621 | Gene ID (NCBI) | 118813 |
| Gene symbol | ZFYVE27 | Synonyms | PROTRUDIN, RP11 459F3.2, SPG33, ZFYVE27 |
Background
ZFYVE27, also named as Protrudin, is a 411 amino acid protein, which contains 1 FYVE-type zinc finger. ZFYVE27 localizes in the recycling endosome membrane and functions as an upstream inhibitor of RAB11, regulating directional protein transport to the forming neurites. ZFYVE27 is a key regulator of vesicular transport during neurite extension and is involved in neuronal intracellular trafficking in the corticospinal tract. |