Product Areas
MUC16,CA125 Antibody
Product Details
Product Information
| Source | Mouse | Purification method | Protein G purification |
| Isotype | IgG1 | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Peptide | Full name | mucin 16, cell surface associated |
|
Calculated molecular weight |
2353 kDa |
Observed molecular
weight |
|
|
GenBank accession number |
NM_024690 | Gene ID (NCBI) | 94025 |
| Gene symbol | MUC16 | Synonyms | CA 125, CA125, FLJ14303, MUC 16, MUC16, Mucin 16 |
Background
MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators. The antibody recognizes the C-term of MUC16. |