Product Areas
PDCD4 Antibody
Product Details
Product Information
| Source: | Mouse | Purify: | Protein G purification |
| IsoType: | IgG1 | Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Immunogen Information
|
Caculated Molecular Weight: |
469aa,52 kDa |
Observed Molecular
Weight: |
56 kDa |
| GenbankNo | BC026104 | GeneID: | 27250 |
| Symbol | PDCD4 | Synonyms | H731, Nuclear antigen H731 like, PDCD4, Protein 197/15a |
Background
Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation, progression and invasion. It was first identified as being differnetially upregulated during apoptosis. Pdcd4 interferes with the activity of the eukaryotic initiation factor (eIF) 4A by displacing the scaffold protein eIF4G from its binding to the RNA helicase eIF4A. |