Product Areas
RPS3 Antibody
Product Details
Product Information
| Source | Mouse | Purification method | Protein A purification |
| Isotype | IgG2a | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
27 kDa |
Observed molecular
weight |
33 kDa |
|
GenBank accession number |
BC003137 | Gene ID (NCBI) | 6188 |
| Gene symbol | RPS3 | Synonyms | 40S ribosomal protein S3, FLJ26283, FLJ27450, ribosomal protein S3, RPS3 |
Background
40S ribosomal protein S3 (RPS3), also named as SW-cl.26, is a 243 amino acid protein,which contains one KH type-2 domain and belongs to the ribosomal protein S3P family. RPS3 localizes in the cytoplasm. RPS3 is identified in a IGF2BP1-dependent mRNP granule complex, which contains untranslated mRNAs. RPS3 plays a role in repairing various DNA damage acting as a repair UV endonuclease. Nuclear accumulation of RPS3 results in an increase in DNA repair activity to some extent, thereby sustaining neuronal survival. |