Product Areas
SLAM/CD150 Antibody
Product Details
Product Information
| Source | mouse | Purification method | Caprylic acid/ammonium sulfate precipitation |
| Isotype | IgM | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
70 kDa |
Observed molecular
weight |
80 kDa |
|
GenBank accession number |
BC012602 | Gene ID (NCBI) | 6504 |
| Gene symbol | SLAMF1 | Synonyms | CD150, CDw150, IPO 3, SLAM, SLAMF1 |
Background
Signaling lymphocytic activation molecule (SLAM, also known as SLAMF1 or CD150) is a 70-kDa transmembrane glycoprotein that belongs to the immunoglobulin gene superfamily. SLAM is constitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation. SLAM is involved in T cell stimulation and cytokine production, and may play an important role in the regulation of immune responses to pathogens. |