Product Areas
SND1 Antibody
Product Details
Product Information
| Source: | Mouse | Purify: | Protein G purification |
| IsoType: | IgG1 | Storage: | PBS with 0.0.2% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Immunogen Information
|
Caculated Molecular Weight: |
101 kDa |
Observed Molecular
Weight: |
101 kDa |
| GenbankNo | BC017180 | GeneID: | 27044 |
| Symbol | SND1 | Synonyms | 100 kDa coactivator, EBNA2 coactivator p100, p100, p100 co activator, SND1, TDRD11 |
Background
Staphylococcal nuclease domain-containing 1 (SND1), is a multifunctional nuclease that consists of four staphylococcal nuclease domains and a tudor domain. SND1 acts as a coactivator that facilitates transcriptional activity of STAT5, 6 and c-Myc. SND1 is a comprising part of the RNA-induced silencing complex(RISC), and takes part in the functions of miRNA, regulates transcription through transcriptional coactivation, RNA interference, RNA splicing, and RNA editing. Higher level of SND1 has been found in colon cancer and prostate cancer, can promote HCC angiogenesis in xenograft model through induction of angiogenic factors. |