Product Areas
TUBB3-specific Antibody
Product Details
Product Information
| Source | Mouse | Purification method | Protein G purification |
| Isotype | IgG1 | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Peptide | Full name | tubulin, beta 3 |
|
Calculated molecular weight |
55 |
Observed molecular
weight |
50-55 kDa |
|
GenBank accession number |
NM_001197181 | Gene ID (NCBI) | 10381 |
| Gene symbol | TUBB3 | Synonyms | beta 4, beta tubulin, MC1R, TUBB, TUBB3, TUBB3-specific, Tubj1, Tubulin beta 3 chain, Tubulin beta III, tubulin, beta 3 |
Background
TUBB3, the class III β tubulin or Tuj1, is selectively expressed in testis and neurons of the central and peripheral nervous system. It has been widely used as a marker for neurons. Aberrant expression of TUBB3 has also been found in various tumors of non-neural origin and can be used as a biomarker for cancer aggressiveness and a marker for the tendency to respond poorly to chemotherapy. This antibody is specific to TUBB3 but not cross-react with other tubulin isoforms. |