Product Areas
Vinculin Antibody
Product Details
Product Information
| Source | Mouse | Purification method | Protein G purification |
| Isotype | IgG1 | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
1133aa,124 kDa |
Observed molecular
weight |
117 kDa |
|
GenBank accession number |
BC039174 | Gene ID (NCBI) | 7414 |
| Gene symbol | VCL | Synonyms | CMD1W, Metavinculin, MVCL, VCL, Vinculin |
Background
Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It plays an important role in cell morphology and locomotion. |