Product Areas
VPS37A Antibody
Product Details
Product Information
| Source | Mouse | Purification method | Protein G purification |
| Isotype | IgG1 | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
|
Calculated molecular weight |
44 kDa |
Observed molecular
weight |
44 kDa |
|
GenBank accession number |
BC022363 | Gene ID (NCBI) | 137492 |
| Gene symbol | VPS37A | Synonyms | ESCRT I complex subunit VPS37A, FLJ32642, FLJ42616, HCRP1, hVps37A, PQBP2, VPS37A |
Background
VPS37A, also named as HCRP1, belongs to the VPS37 family. It is a regulator of vesicular trafficking process. VPS37A is a member of the endosomal sorting complex required for transport (ESCRT) system, in upper motor neuron disease. ESCRT has been shown to play a central role in intracellular trafficking, in the maturation of multivesicular bodies and the sorting of ubiquitinated membrane proteins into internal luminal vesicles. |