Product Areas
YF488 YF488 conjugated CD20 Antibody
Product Details
Product Information
| Source | Mouse | Purification method | Protein G purification |
| Isotype | IgG2b | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Recombinant Protein | Full name | membrane-spanning 4-domains, subfamily A, member 1 |
|
Calculated molecular weight |
297aa,33 kDa |
Observed molecular
weight |
37 kDa |
|
GenBank accession number |
BC002807 | Gene ID (NCBI) | 931 |
| Gene symbol | MS4A1 | Synonyms |
Background
CD20 is a 33-37 kDa transmembrane phosphoprotein. CD20 is a B-lymphocyte surface molecule that is widely expressed during B-cell ontogeny, from early pre-B-cell developmental stages until final differentiation into plasma cells. CD20 functions as calcium-permeable cation channel. It is involved in the regulation of B-cell activation and proliferation. CD20 serves as a useful target for antibody-mediated therapeutic depletion of B-cells. This antibody is conjugated with FY488. |