Vinculin Antibody

Product Details

Product Information
Source Mouse Purification method Protein G purification
Isotype IgG1 Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Calculated molecular
1133aa,124 kDa Observed molecular
117 kDa
GenBank accession
BC039174 Gene ID (NCBI) 7414
Gene symbol VCL Synonyms CMD1W, Metavinculin, MVCL, VCL, Vinculin

Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It plays an important role in cell morphology and locomotion.

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