|Source||Mouse||Purification method||Protein G purification|
|Isotype||IgG1||Storage||PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.|
|BC039174||Gene ID (NCBI)||7414|
|Gene symbol||VCL||Synonyms||CMD1W, Metavinculin, MVCL, VCL, Vinculin|
Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It plays an important role in cell morphology and locomotion.