Product Areas
Lin28B-specific Antibody
Product Details
Product Information
| Source: | Rabbit | Purify: | Antigen affinity purification |
| IsoType: | IgG | Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Immunogen Information
| Immunogen: | Peptide | Full Name: | lin-28 homolog B (C. elegans) |
|
Caculated Molecular Weight: |
28 kDa |
Observed Molecular
Weight: |
|
| GenbankNo | NM_001004317 | GeneID: | 389421 |
| Symbol | LIN28B | Synonyms | CSDD2, FLJ16517, lin 28 homolog B (C. elegans), Lin 28B, Lin28, LIN28B, Protein lin 28 homolog B |
Background
LIN28B, also named as CSDD2, belongs to the lin-28 family. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Lin2B is stage-specifically expressed in embryonic muscle, neurons, and epithelia, as well as in embryonic carcinoma cells; however, it is suppressed in most adult tissues except for skeletal and cardiac muscle. Lin28B shares 78% sequence identity with LIN28A, with some unknown functions. This antibody is specific to LIN28B. |