Product Areas
OCT2-Specific Antibody
Product Details
Product Information
| Source: | Rabbit | Purify: | Antigen affinity purification |
| IsoType: | IgG | Storage: | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles. |
Immunogen Information
| Immunogen: | Peptide | Full Name: | POU class 2 homeobox 2 |
|
Caculated Molecular Weight: |
62 kDa |
Observed Molecular
Weight: |
55 kDa |
| GenbankNo | NM_002698 | GeneID: | 5452 |
| Symbol | POU2F2 | Synonyms | OCT2, Octamer binding protein 2, OTF 2, OTF2, POU class 2 homeobox 2, POU2F2 |
Background
OCT2, also named as POU2F2 and OTF2, belongs to the POU transcription factor family and Class-2 subfamily. OCT2 is a transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). OCT2 regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. It modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. The antibody is specific to OCT2. |