Product Areas
transgelin/SM22-specific Antibody
Product Details
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Peptide | Full name | transgelin |
|
Calculated molecular weight |
22 kDa |
Observed molecular
weight |
22 kDa |
|
GenBank accession number |
NM_003186 | Gene ID (NCBI) | 6876 |
| Gene symbol | TAGLN | Synonyms | SM22, SM22 alpha, SM22a, SM22alpha, Smooth muscle protein 22 alpha, TAGLN, TAGLN1, transgelin, TRANSGELIN 1 |
Background
The transgelin family is a group of proteins that belong to 22kd actin-related corpnin superfamily. Of all three isoforms, transgelin 1 is the best characterized. Transgelin 1, also known as SM22alpha, is a specific marker for differentiated smooth muscle cells. Transgelin 2, also known as SM22 beta, is expressed by both smooth muscle and non-smooth muscle cells in a temporally and spatially regulated pattern. Trangenlin 3, also known as NP25, is only found in highly differentiated neuronal cells. This antibody is speific to transgelin 1. It does not cross-react with transgelin 2 and 3. |